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Dosages

Methionine and SAMe

U.S. RDA:
Not Available

Dr. Atkins:
Depression: 1,500 - 4,000mg of L-methionine.
Parkinson's disease: 1,500 - 4,000mg of L-methionine.
Liver disease: 1,500 - 4,000mg of L-methionine.
Arthritis: 1,500 - 4,000mg of L-methionine.

Dr. Balch:
Adrenal disorders: follow SAMe label directions.
Aging: follow SAMe label directions.
AIDS: follow SAMe label directions.
Alcoholism: 1,000mg of L-methionine, daily, on an empty stomach and SAMe as directed.
Alzheimer's disease: follow SAMe label directions.
Anxiety disorder: 400mg of SAMe twice daily.
Arteriosclerosis/atherosclerosis: 500mg of L-methionine, with L-cysteine and L-carnitine. Take on an empty stomach.
Arthritis: 400mg of SAMe twice daily.
ADD: follow SAMe label directions.
Autism: follow SAMe label directions.
Bulimia: follow SAMe label directions.
Chemical poisoning: 500mg of L-methionine with equal amount of L-cysteine, on an empty stomach.
Circulatory problems: 500mg of L-methionine with equal amount of L-cysteine, on an empty stomach.
Cirrhosis: 500mg of L-methionine with equal amounts of L-arginine, L-cysteine, L-carnitine and glutathione.
Depression: follow SAMe label instructions.
Drug abuse: follow SAMe label instructions.
Emphysema: 500mg of L-methionine with equal amounts L-cysteine and L-glutathione, twice daily.
Environmental toxicity: follow SAMe label directions.
Floaters: follow L-methionine label directions. Take on an empty stomach.
Fibromyalgia syndrome: follow SAMe label directions.
Foodborne/waterborne disease: 500mg with L-cysteine, selenium, SOD, and glutathione.
Fracture: follow SAMe label instructions.
Hepatitis: 500mg of L-methionine and SAMe as directed.
Infertility: follow L-methionine label instructions.
Jaundice: follow SAMe label instructions.
Kidney stones: 500mg of L-methionine, daily, on an empty stomach.
Lead poisoning: follow SAMe label instructions.
Lupus: 500 - 1,000mg of L-methionine with equal amounts L-cysteine and L-lysine.
Obesity: follow L-methionine label directions.
Pregnancy-related problems (morning sickness): 1,000mg of L-methionine daily.
Skin cancer: follow L-methionine label directions.
Sprains, strains, and other injuries: 400mg 2 times daily.

Dr. Barney:
Not Available

Drs. Zand, Spreen, & LaVille:
Depression: 400mg of SAMe three times daily, followed by a maintenance dose of 400mg a day.
Fibrocystic breast disease: 250mg of methionine in a lipotropic combination supplement with choline and inositol.
Fibromyalgia: 400mg of SAMe two or three times daily.
Memory problems: 100 - 300mg of SAMe two or three times daily.
Obesity: 200mg of methionine twice daily as part of a lipotropic combination supplement with choline and inositol.
Pancreatitis: 500mg of methionine twice daily.
Seizure: week 1 - 400mg of SAMe three times daily; week 2 - 400mg of SAMe twice daily; week 3 - reduce to a maintenance dosage or 200mg twice daily.

Integrative Medicine Communications:
Osteoarthritis: 600mg (200 mg tid) of SAMe for the first two weeks and thereafter 400mg (200 mg bid)
for another 22 weeks.
Fibromyalgia: 800mg of SAMe per day for six weeks.
Alcoholic liver disease: 1,200 mg/day of SAMe orally for six months.
Intrahepatic cholestasis: 800 mg/day IV or 1,600 mg/day orally of SAMe.
SAMe should not be taken at night because it may cause restlessness.

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