Supplements

Arginine (L-Arginine)

Arginine is an amino acid that retards the growth of tumors and cancer by enhancing immune function. It decreases the size and activity of the thymus gland, which manufactures T lymphocytes (T cells).

Taking a total of 30 grams over the course of the day, one study showed expanded NK (Natural killer cells) cells' activity by 91%. This type of treatment might prove valuable to people afflicted with AIDS or any other virus or malignant disease.

Supplementation increases the weight of the thymus gland, where immune function originates. More nitric oxide becomes available to the gastrointestinal tract, combating infections and overgrowth of Candida albicans.

Arginine regulates a blood compound called nitric oxide, which is responsible for regulating blood flow, immune function, communication among nerve cells, liver function, blood clotting, and even sexual arousal.

Arginine itself, not the nitric oxide it produces, decreases cholesterol more effectively than any other amino acid. Daily doses of 6-17 grams a day have lowered LDL cholesterol without reducing the beneficial HDL cholesterol, and without side effects. It also promotes healthy coronary microcirculation in people with high cholesterol, and deters the formation of blood clots, which can lead to heart attack or stroke.

Nitric oxide is key in allowing blood vessels to relax, and, thereby controlling high blood pressure. Relaxed arteries mean better blood flow, and circulation-related conditions such as coronary heart disease with angina, intermittent claudication (poor leg circulation), and high blood pressure can benefit from supplementation. Injections of the amino acid can strengthen the cardiac muscle in people with congestive heart failure.

As is true with other building blocks of protein, arginine participates in the maintenance of muscle and lean tissue throughout the body. It can be converted into ornithine, another amino acid. Its presence can stimulate.

In one small study of forty-five older people, a daily tonic containing 17 grams of arginine was shown to preserve lean muscle tissue. The study volunteers who did not receive arginine actually lost lean muscle tissue.

Nitric oxide is a decisive factor in a man's ability to achieve and maintain an erection. Taking 2.8 grams of arginine per day, several studies show, generates enough of the vasodilating compound to help in the treatment of erectile failure. Arginine also increases sperm count in males.

Arginine, research has found, is indispensable in restoring protein balance in severe burn victims. It also speeds wound healing, fractures, and diabetes related foot ulcers.

L-arginine taken in conjunction with L-ornithine can help stimulate weight loss.

Deficiency: Adults, after the age of 30, have an almost complete cessation of arginine secretion from the pituitary gland.

Depleting Agents: Physical trauma increases your need for arginine.

Sources: Arginine is found in nuts, popcorn, carob, gelatin, chocolate, brown rice, oatmeal, raisins, sunflower and sesame seeds, whole wheat bread and all protein-rich foods.

Precautions: Despite all of its benefits, arginine is a free radical, and capable of inflicting oxidative damage. Arginine supplements should be taken with antioxidant protection, including coenzyme Q10 and lipoic acid, which will neutralize the potential harm.

People with viral infections such as herpes should not take supplemental arginine, and should avoid foods rich in arginine and low in the amino acid lysine, as this appears to promote the growth of certain viruses.

L-Arginine supplements should be avoided by pregnant and lactating women.

Persons with schizophrenia should avoid amounts over 30 mg daily. Long-term use, especially of high doses, is not recommended. One study found that several weeks of large doses may result in thickening and coarsening of the skin.

Dosage Ranges and Duration of Administration: For wound healing, helping to restore sexual response, and supporting the immune system, between 1,500 mg and 4 grams per day. (Atkins, et al, 1999)

As part of cardiovascular therapy, 15 grams or more a day might be necessary (Atkins, et al, 1999).